Publikasjoner
NIBIOs ansatte publiserer flere hundre vitenskapelige artikler og forskningsrapporter hvert år. Her finner du referanser og lenker til publikasjoner og andre forsknings- og formidlingsaktiviteter. Samlingen oppdateres løpende med både nytt og historisk materiale. For mer informasjon om NIBIOs publikasjoner, besøk NIBIOs bibliotek.
2025
Sammendrag
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Sammendrag
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Sammendrag
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Sammendrag
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Forfattere
Terje Christensen Are Røysamb Ulrike Bayr Dieu Tien Bui Gudrun Helgadottir Nina Johansen Jörn Klein Mieke C. Louwe Randi Mork Kyungbinn Noh Stefanie Reinhardt Trude Eid Robsahm Kristin Helen Roll Øyvind Steifetten Per Strömberg Gry Tengmark Østenstad Veronika ZaikinaSammendrag
Det er ikke registrert sammendrag
Forfattere
Iuliana Caras Irina-Elena Ionescu Ana-Maria Pantazica Andre van Eerde Hege Særvold Steen Inger Heldal Sissel Haugslien Catalin Tucureanu Raluca-Elena Chelmus Vlad-Constantin Tofan Adriana Costache Adrian Onu Hang Su Norica Branza-Nichita Jihong Liu Clarke Crina StavaruSammendrag
Introduction: Hepatitis B Virus (HBV) infection is still an ongoing public health issue worldwide. The most efficient tool in preventing HBV infection remains vaccination and significant efforts have been made in the last decade to improve current HBV vaccines. Owing to the strict HBV tropism for the human liver, developing animal models for preclinical screening of vaccine candidates is extremely challenging. To date, there are only a few reports regarding the use of humanized mouse models for the evaluation of the immunogenic properties of viral antigens.Methods: Previously we showed that a Nicotiana benthamiana-produced HBV-S/preS116-42 antigen elicited strong HBV-specific immune responses in BALB/c mice. In the current study, we used immunodeficient NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice as recipients of human peripheral blood mononuclear cells (hPBMCs), to evaluate the immunogenicity of the recently developed chimeric HBV immunogen produced in CRISPR/Cas9-edited N. benthamiana, under more “humanized” conditions.Results: Analysis of the immune response in NSG mice immunized with the chimeric antigen demonstrated induction of virus infection-neutralizing antibodies, indicating activation of antigen-specific B cells.Discussion: The ability of hPBMCs-engrafted NSG mice to mount specific humoral immune responses after immunization with viral antigens supports this animal model as a promising tool for pre-clinical evaluation of human vaccine antigens.
Forfattere
Marte Persdatter Tangvik May Bente Brurberg Christer Magnusson Arne Stensvand Simeon RossmannSammendrag
Metabarcoding targeting nematodes, bacteria, fungi and oomycetes was used in combination with multispectral drone imagery and traditional soil extraction of nematodes to diagnose poor growth in patches of a potato field in Norway. Areas of good and poor growth as identified by the normalised difference vegetation index (NDVI) based on aerial photography were compared, and nematodes were identified as the likely drivers of poor growth. This was based on the presence of known plant-parasitic nematodes in the field and the significant association between low alpha diversity (total genus richness and abundance) for nematodes with areas of poor growth, while alpha diversity for other organism groups did not vary between patches with good and poor growth. Metabarcoding represented nematodes well compared to traditional soil extraction. The combination of aerial photography and metabarcoding used in this work offers a promising possibility to identify biological drivers of growth differences across organism groups at field scale.
Forfattere
Linn Vassvik Anders Nielsen Michael P.D. Garratt Bjørn Arild Hatteland Joseph Chipperfield Erik Trond AschehougSammendrag
Low pollinator richness and abundance is a primary driver of pollination deficits and may lead to reduced yields (production deficits). In response, domesticated honeybees are often used to increase pollination success, even though honeybees are less efficient pollinators than naturally occurring wild bees. Here, we explored whether Norwegian apple orchards experience pollination and production deficits, and if such deficits could be related to specific pollinator groups and activity. We conducted a supplemental pollination experiment and measured seed set and yield (fruit set x weight) for three cultivars, in six orchards, in two distinct apple growing regions in central Norway, for two years. In addition, we used cameras to record relative pollinator activity throughout the flowering period. Overall, we found a pollination and production deficit across all cultivars, although there were differences in pollination deficit among cultivars. Three orchards had a pollination deficit both years of the study, suggesting sub-optimal orchard structure and/or a lack of pollinators. However, we found that solitary bees significantly reduced both pollination and production deficit, suggesting that orchard management actions should focus on increasing wild bee diversity and abundance.
Forfattere
Linn Fenna Groeneveld Oksana Bekkevold Trond Bergskås Martin Linkogel Cord Luellmann Marit AlmvikSammendrag
Regulatory bodies aim to protect consumers from harmful substances. The use of certain antibiotics is prohibited in food-producing animals in the EU due to their potential detrimental effects on humans. Among these are nitrofuran antibiotics, which degrade rapidly so that their metabolites are used as markers in screening for their illegal use. The use of one metabolite, semicarbazide (SEM), as a marker for detecting the antibiotic nitrofurazone, has been criticized due to the many pathways it can be formed by and its natural occurrence in some food items. A recent change in the reference point of action (RPA) for SEM, as stated in Commission Regulation (EU) 2019/1871, due to a reassessment of sensitivity of the analyses,poses a problem for the export of heather honey in Norway. Norwegian heather honey seems to exceed the lowered RPA in numerous cases. Here we show that Norwegian heather honey samples, but not polyfloral ‘summer’ honey samples from the same hives, contain SEM. The simplest explanation for the demonstrated pattern is a natural source of SEM in heather honey, not the use of a banned antibiotic. Based on our results, we propose that an exception to the EU regulation should be added, exempting heather honey derived from Calluna vulgaris unless other nitrofurans or their metabolites are found together with SEM.
Forfattere
Jorunn Børve Marcel Wenneker Juliana Perminow May Bente Brurberg Khanh Pham Arne StensvandSammendrag
Bacterial canker caused by Pseudomonas syringae is an important disease on stone fruit trees. The development of infections after artificial inoculation of sweet cherry and plum trees in the nursery phase was examined. Furthermore, sweet cherry trees were observed in a nursery and for up to four years after planting in commercial sweet cherry orchards. If inoculated at the time of grafting, this caused near 100% death of the scions. Following inoculation of defeathering wounds, a mean of 52 and 61% of inoculation sites developed bacterial canker on sweet cherry and plum, respectively. Of non-inoculated nursery trees observed as healthy in the autumn, between 20 and 80% had developed visible bacterial cankers after a period of cold storage. In the planting year, a mean of 21% of the trees developed bacterial canker in seven commercial orchards included in the investigation, and by 2–4 years after planting 40% of the trees had symptoms of the disease. All sweet cherry cultivars and rootstocks developed bacterial canker in the commercial orchards. Cultivar Giorgia had the most severe symptoms. Up to 60% replacement of trees within two years after planting was experienced in the orchards.