Hopp til hovedinnholdet

Publikasjoner

NIBIOs ansatte publiserer flere hundre vitenskapelige artikler og forskningsrapporter hvert år. Her finner du referanser og lenker til publikasjoner og andre forsknings- og formidlingsaktiviteter. Samlingen oppdateres løpende med både nytt og historisk materiale. For mer informasjon om NIBIOs publikasjoner, besøk NIBIOs bibliotek.

2024

Sammendrag

MATKULTUR: Hvorfor velge mat laget av norske råvarer? Spørsmålet var utgangspunkt da studentene ved Nordland fagskoles matkulturstudium stilte til emneprøve på Dønna. NORSKE RESSURSER: Studenter fra Tønsberg i sør til Alta i nord ble utfordret til å vise hvordan det er mulig å utnytte råvarer produsert på norske ressurser. De leverte ifølge forsker og fagansvarlig for studiet, Eva Narten Høberg, en flott, praktisk prøve. - Deltakerne fordypet seg i sei, sild, bygg, sau, melk, rotvekster og potet - og fikk råvarene til å skinne, forteller Høberg. Prøven handlet også om å ta vare på tradisjoner og om bruk av ville vekster nær sagt som en grønn tråd i arbeidet. KREATIVT OG FRISTENDE: - Økt forbruk av norske råvarer er avgjørende for å øke selvforsyningsgraden. Det greide studentene å formidle på en fm måte til gjestene som fikk være med på den avsluttende matopplevelsen.

Til dokument

Sammendrag

Colon cancer is increasing worldwide and is commonly regarded as hormone independent, yet recent reports have implicated sex hormones in its development. Nevertheless, the role of hormones from the hypothalamus–hypophysis axis in colitis-associated colorectal cancer (CAC) remains uncertain. In this study, we observed a significant reduction in the expression of the oxytocin receptor (OXTR) in colon samples from both patient with colitis and patient with CAC. To investigate further, we generated mice with an intestinal-epithelium-cell-specific knockout of OXTR. These mice exhibited markedly increased susceptibility to dextran-sulfate-sodium-induced colitis and dextran sulfate sodium/azoxymethane-induced CAC compared to wild-type mice. Our findings indicate that OXTR depletion impaired the inner mucus of the colon epithelium. Mechanistically, oxytocin was found to regulate Mucin 2 maturation through β1-3-N-acetylglucosaminyltransferase 7 (B3GNT7)-mediated fucosylation. Interestingly, we observed a positive correlation between B3GNT7 expression and OXTR expression in human colitis and CAC colon samples. Moreover, the simultaneous activations of OXTR and fucosylation by l-fucose significantly alleviated tumor burden. Hence, our study unveils oxytocin’s promising potential as an affordable and effective therapeutic intervention for individuals affected by colitis and CAC.

Til dokument

Sammendrag

Parasitic nematodes are ubiquitous and can negatively impact their host by reducing fecundity or increasing mortality, yet the driver of variation in the parasite community across a wildlife host’s geographic distribution remains elusive for most species. Based on an extensive collection of fecal samples (n = 264) from GPS marked moose (Alces alces), we used DNA metabarcoding to characterize the individual (sex, age class) and seasonal parasitic nematode community in relation to habitat use and migration behavior in five populations distributed across a wide latitudinal gradient (59.6◦N to 70.5◦N) in Norway. We detected 21 distinct nematode taxa with the six most common being Ostertagia spp., Nematodirella spp., Trichostongylus spp., T. axei, Elaphostrongylus alces, and an unclassified Strongylida. There was higher prevalence of livestock parasites in areas with larger sheep populations indicating a higher risk of spillover events. The individual level nematode richness was mostly consistent across study areas, while the number and type of nematode taxa detected at each study area varied considerably but did not follow a latitudinal gradient. While migration distance affected nematode beta-diversity across all sites, it had a positive effect on richness at only two of the five study areas suggesting population specific effects. Unexpectedly, nematode richness was higher in winter than summer when very few nematodes were detected. Here we provide the first extensive description of the parasitic nematode community of moose across a wide latitudinal range. Overall, the population-specific impact of migration on parasitism across the distribution range and variation in sympatry with other ruminants suggest local characteristics affect hostparasite relationships. Alces alces Migration Habitat use Moose Nematode diversity

Sammendrag

Agriculture has significantly impacted the land use over the past centuries. For wild herbivores such as the red deer, foraging on farmland can be beneficial when food is limited in their natural habitats. In Norway, the red deer populations consist of migratory and resident individuals, where migrants travel from low-elevation winter ranges, typically with more available farmland, towards higher-elevation summer ranges. Residents remain in the low-elevation areas year-round. I found that residents selected farmland more than migrants, buffering the migrants’ benefit from following the wave of emerging vegetation in spring. Higher farmland availability also delayed the red deer’s spring migration, that generally varied greatly between and within years. Wildlife foraging on farmland can cause conflicts with humans due to reduced crop yield. Grazing can vary with factors on different scales, and I found most variation in grazing between neighbouring meadows, with more grazing on those recently renewed. Within meadows, more grazing was found close to the forest and away from infrastructure. On broad scale, grazing increased with population density. My thesis provides insight into the coupled dynamics of the red deer and agricultural farmlands, which can be important for management of this coupled ecosystem.