Publikasjoner
NIBIOs ansatte publiserer flere hundre vitenskapelige artikler og forskningsrapporter hvert år. Her finner du referanser og lenker til publikasjoner og andre forsknings- og formidlingsaktiviteter. Samlingen oppdateres løpende med både nytt og historisk materiale. For mer informasjon om NIBIOs publikasjoner, besøk NIBIOs bibliotek.
2010
Forfattere
Håvard SteinshamnSammendrag
Literature data from experiments with lactating dairy cows offered silage-based diets was reviewed to evaluate the effects of the grassland legume species Trifolium repens (WC, white clover), Trifolium pratense (RC, red clover) and Medicago sativa (M, lucerne) on feed intake, milk production and milkquality. Seven data sets were created to compare grass silage (G) with grassland legumes in general (L), G with RC, G with WC, G with M, RC with WC, RC with M and different silage proportions of RC. Daily dry matter intake and milk yield were on average 1.6 and 1.6 kg, respectively, higher and milk fat content 1.2 g/kg milk lower on L than on G based diets. Similar differences were found when G was compared with RC or WC diets. Cows offered WC yielded 1.1 kg/d more milk than RC, and milk produced on WC and M contained 0.7 g more protein per kg than milk from RC diets. Increasing the silage diet RC proportion from 0.5 to 1.0 also decreased the milk protein content by 0.8 g/kg milk. RC increased the level of poly-unsaturated fatty acids, particularly C18:3n-3, and isoflavones, particularly equol, in milk. Effects are discussed in relation to plant cell wall characteristics, plant chemical constituents and changes in rumen digestion to explain the origin of the differences in intake, milk yield and milk composition.
Sammendrag
Det er ikke registrert sammendrag
Sammendrag
In this study we investigated the interaction between temperature and genotype on fruit development and levels of total phenols and anthocyanins in cloudberry. The experiment was done in a phytotron using one female (‘Fjellgull") and one hermaphroditic (‘Nyby") cultivar. Plants were grown at 9, 12, 15 and 18°C in 24-h photoperiod. The female cultivars were pollinated with pollen from a male (‘Apollen") clone and from the hermaphrodite clone. Parthenocarpic fruit development was induced by gibberellic acid (GA3). Ripe berries were frozen individually at -80°C and stored until analyses. There was a linear, double logarithmic relationship between temperature and number of days from pollination/GA3-treatment to ripening. ‘Fjellgull" had significantly larger berries than ‘Nyby", and the largest berries were obtained at 12 and 9°C. Pollen clone did not have a significant effect on berry size. GA3 induced parthenogenesis in ‘Fjellgull" and partial parthenogenesis in ‘Nyby". In ‘Fjellgull", the parthenocarpic berries were comparable to pollinated ones at low temperatures, but at 18°C their development was restricted. The level of total anthocyanins was significantly higher in ‘Fjellgull" than in ‘Nyby", and these levels were significantly enhanced at 9 and 12°C compared to higher temperatures. Levels of total phenolic compounds were not significantly affected. In conclusion, the present results indicate that low temperature is favourable both for size and quality of cloudberries.
Forfattere
Bent Håvard Hellum Anita Tøsse Kathrine Høybakk Mette Thomsen Jens Rohloff Odd Georg NilsenSammendrag
Six clones of Rhodiola rosea, obtained from plants originating from widely different areas in Norway, were investigated for their in vitro inhibitory potential on CYP3A4-mediated metabolism and P-gp efflux transport activity. Presumed active constituents in the ethanol extracts of the different clones were quantified. C-DNA baculovirus expressed CYP3A4 and Caco-2 cells were used for inhibitory assays, and as positive control inhibitors ketoconazole and verapamilwere applied, respectively. A validated HPLC methodology was used to quantify the formation of 6-β-OH-testosterone and scintillation counting was used to quantify the transport of 3H-digoxin in Caco-2 cells. All clones showed potent inhibition of CYP3A4 and P-gp activities, with IC50 values ranging from 1.7 to 3.1 μg/mL and from 16.7 to 51.7 μg/ mL, respectively, being below that reported for other herbs and some known classic drug inhibitors, such as St. John’s wort and fluoxetine. Rhodiola rosea might thus be a candidate for clinically relevant drug interactions. The concentration of presumed biologically active constituents in the different clones varied considerably, but this variationwas not related to the clones’ inhibitory potential on CYP3A4 or P-gp activities. Other constituents might thus be responsible for the observed inhibitory properties. The place of origin seemed to be of minor importance for CYP3A4 or P-gp inhibition.
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Forfattere
Ievina SturiteSammendrag
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Forfattere
Ievina SturiteSammendrag
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Forfattere
Anne Kjersti BakkenSammendrag
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