Publikasjoner
NIBIOs ansatte publiserer flere hundre vitenskapelige artikler og forskningsrapporter hvert år. Her finner du referanser og lenker til publikasjoner og andre forsknings- og formidlingsaktiviteter. Samlingen oppdateres løpende med både nytt og historisk materiale. For mer informasjon om NIBIOs publikasjoner, besøk NIBIOs bibliotek.
2010
Forfattere
Ove BergersenSammendrag
Det er ikke registrert sammendrag
Forfattere
Ove BergersenSammendrag
Det er ikke registrert sammendrag
Forfattere
Ove BergersenSammendrag
Det er ikke registrert sammendrag
Sammendrag
Det er ikke registrert sammendrag
Sammendrag
Det er ikke registrert sammendrag
Forfattere
Erik J. JonerSammendrag
Det er ikke registrert sammendrag
Forfattere
Vicki Stone Bernd Nowack Anders Baun Nico van den Brink Frank von der Kammer Maria Dusinska Richard Handy Steven Hankin Martin Hassellöv Erik J. Joner Teresa FernandesSammendrag
Det er ikke registrert sammendrag
Sammendrag
In terrestrial ecotoxicology there is a serious lack of data for potential hazards posed by engineered nanoparticles (ENPs). This is partly due to complex interactions between ENPs and the soil matrix, but also to the lack of suitable toxicological end points in organisms that are exposed to ENPs in a relevant manner. Earthworms are key organisms in terrestrial ecosystems, but so far only physiological end points of low sensitivity have been used in ecotoxicity studies with ENPs. We exposed the earthworm Lumbricus terrestris to silver nanoparticles and measured their impact on apoptosis in different tissues. Increased apoptotic activity was detected in a range of tissues both at acute and sublethal concentrations (down to 4 mg/kg soil). Comparing exposure in water and soil showed reduced bioavailability in soil reflected in the apoptotic response. Apoptosis appears to be a sensitive end point and potentially a powerful tool for quantifying environmental hazards of ENPs.
Forfattere
Hsin-Ho Huang Daniel Camsund Peter Lindblad Thorsten HeidornSammendrag
Cyanobacteria are suitable for sustainable, solar-powered biotechnological applications. Synthetic biology connects biology with computational design and an engineering perspective, but requires efficient tools and information about the function of biological parts and systems. To enable the development of cyanobacterial Synthetic Biology, several molecular tools were developed and characterized: (i) a broad-host-range BioBrick shuttle vector, pPMQAK1, was constructed and confirmed to replicate in Escherichia coli and three different cyanobacterial strains. (ii) The fluorescent proteins Cerulean, GFPmut3B and EYFP have been demonstrated to work as reporter proteins in cyanobacteria, in spite of the strong background of photosynthetic pigments. (iii) Several promoters, like P(rnpB) and variants of P(rbcL), and a version of the promoter P(trc) with two operators for enhanced repression, were developed and characterized in Synechocystis sp. strain PCC6803. (iv) It was shown that a system for targeted protein degradation, which is needed to enable dynamic expression studies, is working in Synechocystis sp. strain PCC6803. The pPMQAK1 shuttle vector allows the use of the growing numbers of BioBrick parts in many prokaryotes, and the other tools herein implemented facilitate the development of new parts and systems in cyanobacteria.
Sammendrag
Emerging compounds are continuously recognized in the environment and many are yet to be evaluated with regard to their environmental level, fate and subsequent biological effects. Most of these chemicals are present at trace level concentration but they can accumulate due to their persitency and special chemical properties. Municipal, hospital, agricultural sewage and leachates from deposits are the major entrance and distribution pathways in environment1-4. Identification and detection of potential sources of emerging compounds in waste water discharges was performed by GC-MS full scan analysis.