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Publikasjoner

NIBIOs ansatte publiserer flere hundre vitenskapelige artikler og forskningsrapporter hvert år. Her finner du referanser og lenker til publikasjoner og andre forsknings- og formidlingsaktiviteter. Samlingen oppdateres løpende med både nytt og historisk materiale. For mer informasjon om NIBIOs publikasjoner, besøk NIBIOs bibliotek.

2009

Sammendrag

Målet med gjødslinga i potet er å oppnå et høyt avlingsnivå og riktig kvalitet til potetene. Gjødselpraksisen må være til minst mulig belastning på miljøet. Dette må ikke gå på bekostning av kvalitetskravene de ulike produksjoner har. En nøye gjennomtenkt gjødselplan er det beste verktøyet for å oppnå dette.

Til dokument

Sammendrag

Six clones of Rhodiola rosea, obtained from plants originating from widely different areas in Norway, were investigated for their in vitro inhibitory potential on CYP3A4-mediated metabolism and P-gp efflux transport activity. Presumed active constituents in the ethanol extracts of the different clones were quantified. C-DNA baculovirus expressed CYP3A4 and Caco-2 cells were used for inhibitory assays, and as positive control inhibitors ketoconazole and verapamilwere applied, respectively. A validated HPLC methodology was used to quantify the formation of 6-β-OH-testosterone and scintillation counting was used to quantify the transport of 3H-digoxin in Caco-2 cells. All clones showed potent inhibition of CYP3A4 and P-gp activities, with IC50 values ranging from 1.7 to 3.1 μg/mL and from 16.7 to 51.7 μg/ mL, respectively, being below that reported for other herbs and some known classic drug inhibitors, such as St. John’s wort and fluoxetine. Rhodiola rosea might thus be a candidate for clinically relevant drug interactions. The concentration of presumed biologically active constituents in the different clones varied considerably, but this variationwas not related to the clones’ inhibitory potential on CYP3A4 or P-gp activities. Other constituents might thus be responsible for the observed inhibitory properties. The place of origin seemed to be of minor importance for CYP3A4 or P-gp inhibition.

Sammendrag

At bregnen strutseving er spiselig er ikke så godt kjent. At den også er en svært næringsrik plante burde få flere til å bruke den. Strutseving er en godt synlig bregne i den norske natur. Den kan bli rundt 2 m høy og vokser ofte i store grupper. Den forekommer i lavlandet i det meste av Norge, men er mindre vanlig i ytre Agder, Rogaland og Finmark (Lid og Lid 1994). For øvrig forekommer den sirkumboreal i et belte rundt den nordlige halvkulen gjennom Europa, Asia og Nordamerika. Det latinske navn er Matteúccia struthiópteris (L.) Tod. På norsk kjennes planten bl.a. under navnet strutseving eller bispestav, og på engelsk Ostrich fern og "fiddleheads". Strutseving og Ostrich fern kommer fra det latinske struthiópteris og refererer til formen på de utvokste bladene, mens navnet bispestav og det engelske fiddelheads viser til formen på de spiselige nye skudd. http://www.skogoglandskap.no/Artsbeskrivelser/strutseving

Til dokument

Sammendrag

The flavonoid pathway is known to be up-regulated by different environmental stress factors. Down-regulation of the pathway is much less studied and is emphasized in the present work. Flavonoid accumulation was induced by exposing plants for 1 week to nitrogen depletion at 10 degrees C, giving high levels of anthocyanins and 3-glucoside-7-rhamnosides, 3,7-di-rhamnosides and 3-rutinoside-7-rhamnosides of kaempferol and quercetin. Flavonol accumulation as influenced by temperatures and nitrogen supply was not related to the glycosylation patterns but to the classification as quercetin and kaempferol. When nitrogen was re-supplied, transcripts for main regulators of the pathway, PAP1/GL3 and PAP2/MYB12, fell to less than 1 and 0.1% of initial values, respectively, during 24 h in the 15-30 degrees C temperature range. Anthocyanins showed a half-life of approximately 1 d, while the degradation of flavonols was much slower. Interestingly, the initial fluxes of anthocyanin and flavonol degradations were found to be temperature-independent. A kinetic model for the flavonoid pathway was constructed. In order to get the observed concentration-temperature profiles as well as the temperature compensation in the flavonoid degradation flux, the model predicts that the flavonoid pathway shows an increased temperature sensitivity at the end of the pathway, where the up-regulation by PAP/GL3 has been found to be largest.