Publikasjoner
NIBIOs ansatte publiserer flere hundre vitenskapelige artikler og forskningsrapporter hvert år. Her finner du referanser og lenker til publikasjoner og andre forsknings- og formidlingsaktiviteter. Samlingen oppdateres løpende med både nytt og historisk materiale. For mer informasjon om NIBIOs publikasjoner, besøk NIBIOs bibliotek.
2023
Authors
Thomas Solvin Inger Sundheim Fløistad Gunnar Friis Proschowsky Torben Leisgaard Tiina Ylioja Marko Tynkkynen Brynjar Skúlason Hallur S. Björgvinsson Espen Stokke Marte Friberg Myhre Ellinor Edvardsson Claes UgglaAbstract
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Authors
Finn-Arne HaugenAbstract
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Authors
Kristina Bringedal GeddeAbstract
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Authors
Gabriella do Vale Pereira Luis E. C. Conceição Filipe Soares Jessica Petereit Bela H. Buck Johan Johansen Jorge Dias Filippo FaccendaAbstract
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Authors
Caroline Chylinski Kristin Fløgstad Degnes Inga Marie Aasen Sokratis Ptochos Berit Marie Blomstrand Karl-christian Mahnert Heidi L Enemark Stig Milan Thamsborg Håvard Steinshamn Spiridoula AthanasiadouAbstract
The antiparasitic potential of plants could offer a vital solution to alleviating the costs of gastrointestinal nematode (GIN) infections in ruminant production globally. Leveraging known bioactive molecules, however, is complex, where plant species, extraction processes and seasonality impact bioavailability and efficacy. This study assessed the impact of a comprehensive set of factors on the antiparasitic activity of Norwegian conifers to identify bark compounds specific against GIN. Antiparasitic activity was determined using in vitro assays targeting morphologically distinct life stages of ovine GIN: the egg hatch assay and larval motility assay. In depth characterisation of the chemical composition of the bark extracts was carried out using chromatographic separation, UV-absorbance, and molecular mass profiles to identify compounds implicated in the activity. Three key findings emerged: (1) the activity of bark extracts varied markedly from 0 to 100% antiparasitic efficacy, owing to tree species, extraction solvent and seasonality; (2) the GIN exhibited species-and stage-specific susceptibility to the bark extracts; (3) the presence of condensed tannins, amongst other compounds, was associated with anthelmintic activity. These findings add new insights into urgently needed alternative parasite control strategies in livestock.