Publications
NIBIOs employees contribute to several hundred scientific articles and research reports every year. You can browse or search in our collection which contains references and links to these publications as well as other research and dissemination activities. The collection is continously updated with new and historical material.
2022
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Kristina Bringedal GeddeAbstract
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Maryam Mirahmad Shahrzad Mohseni Ozra Tabatabaei-Malazy Fataneh Esmaeili Sudabeh Alatab Roodabeh Bahramsoltani Hanieh-Sadat Ejtahed Husseyn Qulami Zahra Bitarafan Babak Arjmand Elahe NazeriAbstract
Background Inflammation is a double-edged sword in the pathophysiology of chronic diseases, such as type 2 diabetes mellitus (T2DM). The global rise in the prevalence of T2DM in one hand, and poor disease control with currently-available treatments on the other hand, along with an increased tendency towards the use of natural products make scientists seek herbal medicines for the management of diabetes and its complications by reducing C-reactive protein (CRP) as an inflammatory marker. Purpose To systematically review the literature to identify the efficacy of various medicinal plants with antioxidative and anti-inflammatory properties considering their effect on CRP in animal models of T2DM. Study design systematic review. Methods Electronic databases including PubMed, Scopus, Web of Science and Cochran Library were searched using the search terms “herbal medicine”, “diabetes”, “c-reactive protein”, “antioxidants” till August 2021. The quality of evidence was assessed using the Systematic Review Centre for Laboratory animal Experimentation (SYRCLE's) tool. The study protocol was registered in PROSPERO with an ID number CRD42020207190. A manual search to detect any articles not found in the databases was also made. The identified studies were then critically reviewed and relevant data were extracted and summarized. Results Among total of 9904 primarily-retrieved articles, twenty-three experimental studies were finally included. Our data indicated that numerous herbal medicines, compared to placebo or hypoglycemic medications, are effective in treatment of diabetes and its complications through decreasing CRP concentrations and oxidative stresses levels. Medicinal plants including Psidium guajava L., Punica granatum L., Ginkgo biloba L., Punica granatum L., Dianthus superbusn L.. Moreover, Eichhornia crassipes (Mart.) Solms, Curcuma longa L., Azadirachta indica A. Juss., Morus alba L., and Ficus racemosa L. demonstrated potential neuroprotective effects in animal models of diabetes. Conclusion Hypoglycemic medicinal plants discussed in this review seem to be promising regulators of CRP, and oxidative stress. Thus, these plants are suitable candidates for management of diabetes’ complications. Nevertheless, further high-quality in vivo studies and clinical trials are required to confirm these effects.
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Yong Q. Tian Qian Yu Hunter J. Carrick Brian L. Becker Remegio Confesor Mark Francek Olivia C. AndersonAbstract
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Daniel Kpienbaareh R. Bezner Kerr Hanson Nyantakyi-Frimpong Daniel Amoak Katja Poveda Sekhar Udaya Nagothu Cassandra Vogel Aaron Iverson Mehreteab Tesfai Isaac Luginaah Ingolf Steffan-Dewenter Jinfei Wang Georg Küstner Stephanie Enloe Vera Mayer Laifolo Dakishoni Esther Lupafya Lizzie Shumba Timothy Chunga Penjani Kanyimbo Petros Munthali Tinkani Gondwe Innocent Mhoni Mwapi Mkandawire Tapiwa Mkandawire Pressings Moyo Yolice TemboAbstract
How can agroecological research methods effectively engage smallholder farmers, who provide over half of the world’s food supply, and whose farm management activities have significant impacts on biodiversity and ecosystem services? This question is highly relevant in Malawi where the research took place, but in other low-income countries in Africa with mostly agrarian populations, in which multi-scalar processes drive high food insecurity, alongside declining biodiversity, worsening land degradation and climate change. We analyse an innovative transdisciplinary agroecological approach that attempts to bridge the science-practice-policy gap by examining the potential of agro-ecological measures to enhance functional biodiversity and ecosystem services. This study involves a longitudinal, case-control and participatory research design in a region where thousands of farmers have experimented with agroecological practices, e.g., legume intercropping, composting, and botanical sprays. Innovative transdisciplinary agroecological research activities involved farmer participatory research, ecological monitoring and field experiments, social science methods (both qualitative and quantitative), participatory methodologies (public participatory Geographic Information Systems - PPGIS and scenario planning and testing) and stakeholder engagement to foster science-policy linkages. We discuss the theoretical and methodological implications of this novel transdisciplinary and participatory approach about pluralism, decolonial and translational ecological research to foster sustainability and climate resilience of tropical farming systems.
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Johanna Eva Bodin Nur Duale Anne-Marthe Ganes Jevnaker Monica Sanden Ville Erling Sipinen Tage Thorstensen Rose VikseAbstract
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